Arsenal could be without seven first team players for their trip to Watford in the Premier League this weekend.
Shkodran Mustafi limped off in Germany's 5-1 win over Azerbaijan on Sunday, and could miss the club's next seven fixtures.
The defender suffered a torn ligament, and had to be helped off the pitch before being replaced just 36 minutes in the game.
Meanwhile Laurent Koscielny, who has been sidelined for the Gunners over the past few weeks, is facing a race to be fit for Saturday's game.
The France centre-back injured his Achilles and missed out on his nation's 1-0 win over Bulgaria last time out, but could return this weekend.
Mesut Ozil (knee), Francis Coquelin (hamstring) and Danny Welbeck (groin strain) are all also hoping to be fit for the match.
But Wenger will be cautious not to rush back any one player for fear of creating further injury problems later down the line.
Calum Chambers on the other hand is not in contention for the clash. He is suffering a knee injury that will keep him out until the end of the month.
While Santi Cazorla will be out until the new year after suffering Achilles problems all the way back in October 2016.